Permission to Care for Ourselves

Exposing ourselves to art.

Background: Apolipoprotein B-100 (apo B-100) stands as one of the largest proteins in humans. Its large size of 4536 amino acids hampers the production of X-ray diffraction quality crystals and hinders in-solution NMR analysis, and thus necessitates a domain-based approach for the structural characterization of the multi-domain full-length apo B. Results: The structure of apo B-17 (the N-termin...

How to Ask for Permission

Application platforms provide applications with access to hardware (e.g., GPS and cameras) and personal data. Modern platforms use permission systems to protect access to these resources. The nature of these permission systems vary widely across platforms. Some platforms obtain user consent as part of installation, while others display runtime consent dialogs. We propose a set of guidelines to ...

Learning to tolerate ourselves

2 JEM Vol. 206, No. 1, 2009 Learning to tolerate ourselves On age 139, Duty et al. find self-reactive B cells in healthy adults that might harm their own body if given the chance. Checkpoints during B cell development ensure that immune cells won’t confuse the self for an intruder. At birth, many B cells express self-reactive receptors. Most of the...

Ourselves

Why are we not taking care of ourselves?